Determination of the quantitative content of procyanidins in hawthorn fruits

Authors

  • N. V. Sydora National University of Pharmacy, Ukraine
  • A. M. Kovalyova National University of Pharmacy, Ukraine
  • I. A. Danylova National University of Pharmacy, Ukraine

DOI:

https://doi.org/10.24959/ophcj.18.955

Keywords:

hawthorn, fruits, procyanidins

Abstract

Aim. To determine the quantitative content of procyanidins in hawthorn fruits.

Results and discussion. It was found that the quantitative content of procianidinsin Crataegus succulentha Sarg. fruits was 1.45 % ± 0.02; C. prunifolia Sarg. – 1.24 % ± 0.05; C. pseudokyrtostila Klok. – 1.15 % ± 0.03; C. leiomonogyna Klok. – 1.28 % ± 0.04; C. arnoldii Sarg. – 1.38 %± 0.02; C. submollis Sarg. – 1.37 % ± 0.03; C. mollis Sarg. 1.48 % ± 0.01.

Ехperimental part. The content of procyanidins was determined by the spectrophotometric method calculated with the reference to cyanidin chloride. The optical density of the test solution was measured at a wavelength of 545 nm. The study was performed on a Thermo Fisher Scientific model EVOVUTION 60S spectrophotometer.

Conclusions. Procyanidins of fruits of 7 nonofficinal species of the genus Crataegus L. have been studied. It has been determined that all samples under research meet the requirements of the SPhU and EuPh by the indicator “Assay for procyanidins”, which should be at least 1 %.

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References

  1. Honcharov, N. F., Sidora, N. V., Kovaleva, A. M., Komissarenko, A. N. (2008). Rossiyskiy mediko-biologicheskiy vestnik imeni akademica Pavlova, 3, 150–154.
  2. Kumar, D., Arya, V., Bhat, Z. A., Khan, N. A., & Prasad, D. N. (2012). The genus Crataegus: chemical and pharmacological perspectives. Revista Brasileira de Farmacognosia, 22 (5), 1187–1200. https://doi.org/10.1590/s0102-695x2012005000094
  3. Santos-Buelga, C., Scalbert, A. (2000). Proanthocyanidins and tannin compounds - nature, occurrence, dietary intake and effects on nutrition and health. J. Sci. Food Agric, 80 (7), 1094–1117. https://doi.org/10.1002/(sici)1097-0010(20000515)80:7<1094::aid-jsfa569>3.0.co;2-1
  4. Kovaleva, A. M., Sydora, N. V., Komisarenko, A. M., Honcharov, M. F. (2008). Medychna khimiia, 3, 110–112.
  5. 5. European Pharmacopoeia (7-ed). (2010), 1, 1147–1148.
  6. Fine, A. M. (2000). Oligomeric proanthocyanidin complexes: history, structure, and phytopharmaceutical applications. Altern. Med. Rev., 5 (2), 144–151.
  7. Mraihi, F., Hidalgo, M., de Pascual-Teresa, S., Trabelsi-Ayadi, M., & Chérif, J.-K. (2015). Wild grown red and yellow hawthorn fruits fromTunisiaas source of antioxidants. Arabian Journal of Chemistry, 8 (4), 570–578. https://doi.org/10.1016/j.arabjc.2014.11.045
  8. Barros, L., Carvalho,A. M., Ferreira, I.C. (2010). Comparing the composition and bioactivity of Crataegus monogyna flowers and fruits used in folk medicine. Phytochemical Analysis, 22, 181–188. https://doi.org/10.1002/pca.1267
  9. 9. Derzhavna Farmakopeia Ukrainy. (1-nded.). (2008). Kharkiv: Ukrainskyi naukovyi farmakopeinyi tsentr yakosti likarskykh zasobiv, 414–417.
  10. Khishova, O. M., & Buzuk, G. N. (2006). Quantitative determination of procyanidins in hawthorn fruits. Pharmaceutical Chemistry Journal, 40(2), 79–81. https://doi.org/10.1007/s11094-006-0063-1

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Published

2018-12-14

How to Cite

(1)
Sydora, N. V.; Kovalyova, A. M.; Danylova, I. A. Determination of the Quantitative Content of Procyanidins in Hawthorn Fruits. J. Org. Pharm. Chem. 2018, 16, 48-51.

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Section

Original Researches