The antioxidant activity of pyridylhydrazones of aromatic aldehydes
The kinetic parameters of the antioxidant activity of pyridylhydrazones derivatives of aromatic aldehydes in the initiated oxidation of ethylbenzene have been determined by the chemiluminescent method. The antioxidants studied have higher values of the reaction rate constants with peroxy radicals k7 compared to ionol. In the conditions of autooxidation of ethylbenzene the efficiency of the antioxidants studied reduces. It has been found that 3-pyridylhydrazon-3,5-dimethyl-4-hydroxybenzaldehyde interacts with cumene hydroperoxide. The regularities of the inhibitory effect of pyridylhydrazones in heterogeneous systems have been studied. Interaction of pyridylhydrazones with НО• radicals has been investigated by the chemiluminescent method in water solution. It has been determined that pyridylhydrazones show a high activity towards НО• radicals. In the initiated azodiisobutyronitrile oxidation the emulsion of ethylbenzene : water derivative of pyridylhydrazones has revealed a high antioxidant activity. In the presence of hydrophobic derivatives in molecules of antioxidants the values of log P and the induction period (τ/τ0) increase. When inhibiting the initiated oxidation of phosphatidylcholine dispersion pyridylhydrazones show practically twice higher antioxidant activity in comparison with ionol.
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