Vol. 17 No. 3(67) (2019)

Original researches

• The search for potential inhibitors of protein kinase Pim-1 among new amides of 1,2,4-triazolo[4,3-a]pyridine-3-metanamin with the 1,2,4-oxadiazol cycle in position 7 and 8

  V. R. Karpina, S. M. Kovalenko, O. V. Zaremba, O. V. Silin, V. V. Ivanov, S. S. Kovalenko, T. Langer

  5-14

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• Synthesis and antioxidant properties of novel thiazolo[4,5-b]pyridine-2-ones

  T. I. Chaban, Yu. E. Matiychuk, V. V. Ogurtsov, I. G. Chaban, V. S. Matiychuk

  15-20

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• Synthesis and the biological activity of bis-mefenamidocalixarene

  N. M. Chalenko, R. V. Rodik, G. O. Syrova

  21-25

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• The study of the antimicrobial activity of the derivatives of 6-(1,2,4-oxadizol-3-yl)- and 6-(2-aminothiazol-4-yl)thieno[2,3-d]pyrimidin-4-ones by the double dilution method

  S. V. Vlasov, S. M. Kovalenko, T. P. Osolodchenko, V. S. Vlasov

  26-30

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• The acid-base properties of 2-(benzoylamino)(1-R-2-oxoindolin-3-ylidene)acetic acids

  S. V. Kolisnyk, O. M. Svechnikova, O. O. Altukhov, O. V. Kolisnyk, O. F. Vynnyk

  31-34

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• Development and validation of the enzymatic kinetic photometric procedure for determination of residual quantities of dequalinium chloride on the surface of the pharmaceutical equipment

  M. Ye. Blazheyevskiy, O. V. Kovalska, Ye. O. Tsapko, D. D. Shapovalenko

  35-43

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• The comparative quantum chemical study of the epoxidation reaction mechanism of eugenol and isoeugenol with peracetic and perbenzoic acids

  O. M. Agafonov, S. I. Okovytyy, M. Ye. Blazheyevskiy

  44-50

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• Development and validation of the HPLC-procedure for the quantitative determination of isosorbide dinitrate in matrix granules

  D. S. Oleynikov, A. G. Kaplaushenko

  51-58

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