The study of the qualitative composition and the quantitative content of phenolic compounds in dietary supplements with lingonberry

Authors

DOI:

https://doi.org/10.24959/ophcj.21.243782

Keywords:

lingonberry, spectrophotometry, analysis, phenolic compounds, dietary supplements

Abstract

Aim. Today, there are a lot of dietary supplements with lingonberry at the pharmaceutical market of Ukraine; therefore, the analysis and quality control of these products are relevant. In this connection, the aim of the research was to study the qualitative composition and determine the quantitative content of phenolic compounds in dietary supplements with lingonberry.
Materials and methods. Such dietary supplements as “Extract of lingonberry” (MEDAGROPROM), “Lingonberry” (Danikafarm), “Lingonberry nano” (LSS SYSTEM) were chosen for the study. The qualitative analysis was performed by thin layer chromatography (TLC), spectrophotometry was used for the quantitative determination.
Results and discussion. Hydroquinone derivatives, flavonoids and hydroxycinnamic acids were found in the dietary supplements analyzed. The total content of phenolic compounds was 8.70, 0.26, 0.30 %, flavonoids – 6.37, 0.15, 0.12 %, hydroxycinnamic acids – 0.94, 0.06, 0.13 %, and hydroquinone derivatives – 1.01, 0.04, 0.03 % in such dietary supplements as “Extract of lingonberry” (MEDAGROPROM), “Lingonberry” (Danikafarm), “Lingonberry nano” (LSS SYSTEM), respectively.
Conclusions. The qualitative and quantitative analysis of the dietary supplements with lingonberry analyzed has been performed. “Extract of lingonberry” (MEDAGROPROM) dietary supplement meets the requirements of the State of Pharmacopoeia of Ukraine 2.0, whereas “Lingonberry” (Danikafarm) and “Lingonberry nano” (LSS SYSTEM) do not. Based on the results of the study it can be concluded that the problem of compliance of dietary supplements is relevant today and requires the introduction of regulatory documentation for the detection and determination of biologically active substances in dietary supplements.

Supporting Agency

  • The work is a part of the studies of the National University of Pharmacy on the topic “Organic synthesis and analysis of biologi- cally active compounds, drug development on the basis of synthetic substances” (the state registration No. 01144000943; the research period – 2019 – 2024).

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Published

2022-03-23

How to Cite

(1)
Maslov, O. Y.; Komisarenko , M. A.; Kolisnyk, . S. V.; Antonenko, O. V.; Kolisnyk, O. V.; Kostina, T. A. The Study of the Qualitative Composition and the Quantitative Content of Phenolic Compounds in Dietary Supplements With Lingonberry. J. Org. Pharm. Chem. 2022, 19, 40-46.

Issue

Vol. 19 No. 4(76) (2021)

Section

Original Researches

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