The Quantitative Determination of Etonium by the Enzymatic Kinetic-Spectrophotometric Method

Authors

DOI:

https://doi.org/10.24959/ophcj.24.304120

Keywords:

surfactant, ethonium, cholinesterase, acetylcholine

Abstract

The use of the cholinesterase enzyme as a component of the analytical system has made it possible to develop a new kinetic-spectrophotometric method, which is alternative to the pharmacopoeial method, for determining the quaternary ammonium salt – ethonium in the substance and a dosage form. This method is characterized by high sensitivity and specificity, and is relatively cheap. The relative standard deviation of the procedure does not exceed 2.7 %, and the limit of quantification is 17 ng mL–1.

Supporting Agency

  • The authors received no specific funding for this work.

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References

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Published

2024-05-14

How to Cite

(1)
Blazheyevskiy, M. Y.; Kovalska, O. V. The Quantitative Determination of Etonium by the Enzymatic Kinetic-Spectrophotometric Method. J. Org. Pharm. Chem. 2024, 22, 57-62.

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Original Researches