High-Temperature Polymer Components Reimagined: Scalable Syntheses and de novo Routes to Structurally Versatile Precursors

Authors

  • Roman M. Kurganov Enamine Ltd; Institute of Organic Chemistry of the National Academy of Sciences of Ukraine; V. Bakul Institute for Superhard Materials of the National Academy of Sciences of Ukraine , Ukraine
  • Oleh V. Svaliavyn Enamine Ltd; Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, Ukraine https://orcid.org/0009-0004-0692-691X
  • Yevgen O. Pashchenko V. Bakul Institute for Superhard Materials of the National Academy of Sciences of Ukraine, Ukraine https://orcid.org/0000-0001-5545-5780
  • Denis O. Savchenko V. Bakul Institute for Superhard Materials of the National Academy of Sciences of Ukraine, Ukraine https://orcid.org/0000-0002-9474-3993
  • Alexander B. Rozhenko Enamine Ltd; Taras Shevchenko National University of Kyiv; Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, Ukraine https://orcid.org/0000-0003-4022-7851
  • Serhiy V. Ryabukhin Enamine Ltd; Taras Shevchenko National University of Kyiv; Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, Ukraine https://orcid.org/0000-0003-4281-8268
  • Dmitriy M. Volochnyuk Enamine Ltd; Taras Shevchenko National University of Kyiv; Institute of Organic Chemistry of the National Academy of Sciences of Ukraine, Ukraine https://orcid.org/0000-0001-6519-1467

DOI:

https://doi.org/10.24959/ophcj.24.317091

Keywords:

heat-resistant polymers, monomers, oligomers, curing agents, triazine, phthalonitrile, borosilane, diamine, synthesis

Abstract

Developing efficient and scalable synthetic protocols for key polymer precursors is crucial to advancing high-performance materials designed to withstand severe thermal environments. In this article, we report on the development of solid, high-yield methods for preparing structurally diverse building blocks, including s-triazine derivatives, phenyl-borosilane alkynyl oligomers, phthalonitrile-based monomers, and novel diamine curing agents on multi-gram to multi-hundred-gram scales. These carefully optimized procedures use readily available starting materials, mild conditions, and well-known synthetic transformations, thus addressing the longstanding challenges associated with their practical upscaling. The resulting library of monomers and oligomers offers a broad range of reactive functional groups (e.g., nitriles, alkynes, borosilane motifs), enabling future combinatorial-like strategies for the formation of advanced co-polymers with enhanced thermal stability, mechanical strength, and tunable properties suitable for high-temperature applications.

Supporting Agency

  • The work was supported by the Ministry of Education and Science of Ukraine (grant No. 1/РН/25-024).

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Published

2024-12-27

How to Cite

(1)
Kurganov, R. M.; Svaliavyn, O. V.; Pashchenko, Y. O.; Savchenko, D. O.; Rozhenko, A. B.; Ryabukhin, S. V.; Volochnyuk, D. M. High-Temperature Polymer Components Reimagined: Scalable Syntheses and De Novo Routes to Structurally Versatile Precursors. J. Org. Pharm. Chem. 2024, 22, 46-55.

Issue

Vol. 22 No. 3 (2024)

Section

Advanced Researches

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