Biocatalytic Approach to Aldehydes Using Lyophilisates of Bjerkandera Adusta Fungus

Authors

  • Vladislav Ya. Shah Faculty of Chemical Technology, National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”, Ukraine
  • Valeriia Nikitenkova Institute of Food Chemistry and Food Biotechnology, Justus Liebig University Giessen, Ukraine https://orcid.org/0000-0002-8229-457X
  • Yuliia R. Kurtash Faculty of Chemical Technology, National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”, Ukraine
  • Tetiana A. Krupodorova Department of Plant Food Products and Biofortification, Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine, Ukraine https://orcid.org/0000-0002-4665-9893
  • Tetiana S. Zhuk Faculty of Chemical Technology, National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”; Institute of Food Chemistry and Food Biotechnology, Justus Liebig University Giessen, Ukraine https://orcid.org/0000-0001-5184-704X

DOI:

https://doi.org/10.24959/ophcj.25.340347

Keywords:

biocatalytic oxidation, benzylic alcohols, allylic alcohols, fungal biocatalysis, mild oxidation

Abstract

An optimized biocatalytic oxidation protocol has been developed for the efficient conversion of benzylic and allylic alcohols into their corresponding aldehydes. The sustainable method uses lyophilized mycelia of Bjerkandera adusta white-rot fungus as a catalyst in the aqueous medium with 2-propanol (10% v/v) as a co-solvent, and operates under mild conditions to give high yields for a wide range of substrates. On a preparative scale, the approach allowed the synthesis of important aldehydes, including benzaldehyde, piperonal, cinnamaldehyde, cuminaldehyde, methoxybenzaldehydes, and citral.

Supporting Agency

  • The authors received no specific funding for this work.

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Published

2026-04-07

How to Cite

(1)
Shah, V. Y.; Nikitenkova, V.; Kurtash, Y. R.; Krupodorova, T. A.; Zhuk, T. S. Biocatalytic Approach to Aldehydes Using Lyophilisates of Bjerkandera Adusta Fungus. J. Org. Pharm. Chem. 2026, 23, 57-63.

Issue

Vol. 23 No. 4 (2025)

Section

Original Researches

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